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Glutaminase inhibition in renal cell carcinoma therapy

Receptor tyrosine kinase inhibitors have been a standard first-line therapy for renal cell carcinoma (RCC) for over a decade. Although they stabilize the disease, they are unable to remove all tumor cells, leading to relapse. Moreover, both intrinsic and acquired resistance to therapy are a signific...

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Detalles Bibliográficos
Autores principales: Raczka, Aleksandra M., Reynolds, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992627/
https://www.ncbi.nlm.nih.gov/pubmed/35582719
http://dx.doi.org/10.20517/cdr.2018.004

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