Emerging targets in cancer drug resistance

Drug resistance is a complex phenomenon that frequently develops as a failure to chemotherapy during cancer treatment. Malignant cells increasingly generate resistance to various chemotherapeutic drugs through distinct mechanisms and pathways. Understanding the molecular mechanisms involved in drug...

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Detalles Bibliográficos
Autores principales: Kumar, Shashank, Kushwaha, Prem Prakash, Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992633/
https://www.ncbi.nlm.nih.gov/pubmed/35582722
http://dx.doi.org/10.20517/cdr.2018.27
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author Kumar, Shashank
Kushwaha, Prem Prakash
Gupta, Sanjay
author_facet Kumar, Shashank
Kushwaha, Prem Prakash
Gupta, Sanjay
author_sort Kumar, Shashank
collection PubMed
description Drug resistance is a complex phenomenon that frequently develops as a failure to chemotherapy during cancer treatment. Malignant cells increasingly generate resistance to various chemotherapeutic drugs through distinct mechanisms and pathways. Understanding the molecular mechanisms involved in drug resistance remains an important area of research for identification of precise targets and drug discovery to improve therapeutic outcomes. This review highlights the role of some recent emerging targets and pathways which play critical role in driving drug resistance.
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spelling pubmed-89926332022-05-16 Emerging targets in cancer drug resistance Kumar, Shashank Kushwaha, Prem Prakash Gupta, Sanjay Cancer Drug Resist Review Drug resistance is a complex phenomenon that frequently develops as a failure to chemotherapy during cancer treatment. Malignant cells increasingly generate resistance to various chemotherapeutic drugs through distinct mechanisms and pathways. Understanding the molecular mechanisms involved in drug resistance remains an important area of research for identification of precise targets and drug discovery to improve therapeutic outcomes. This review highlights the role of some recent emerging targets and pathways which play critical role in driving drug resistance. OAE Publishing Inc. 2019-06-19 /pmc/articles/PMC8992633/ /pubmed/35582722 http://dx.doi.org/10.20517/cdr.2018.27 Text en © The Author(s) 2019. https://creativecommons.org/licenses/by/4.0/© The Author(s) 2019. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Kumar, Shashank
Kushwaha, Prem Prakash
Gupta, Sanjay
Emerging targets in cancer drug resistance
title Emerging targets in cancer drug resistance
title_full Emerging targets in cancer drug resistance
title_fullStr Emerging targets in cancer drug resistance
title_full_unstemmed Emerging targets in cancer drug resistance
title_short Emerging targets in cancer drug resistance
title_sort emerging targets in cancer drug resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992633/
https://www.ncbi.nlm.nih.gov/pubmed/35582722
http://dx.doi.org/10.20517/cdr.2018.27
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AT kushwahapremprakash emergingtargetsincancerdrugresistance
AT guptasanjay emergingtargetsincancerdrugresistance

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