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Association of the Protein-Quality-Control Protein Ubiquilin-1 With Alzheimer’s Disease Both in vitro and in vivo

Alzheimer’s disease (AD) belongs to a class of diseases characterized by progressive accumulation and aggregation of pathogenic proteins, particularly Aβ proteins. Genetic analysis has identified UBQLN1 as an AD candidate gene. Ubiquilin-1 levels reduce with AD progression, suggesting a potential lo...

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Detalles Bibliográficos
Autores principales:	Zhang, Can, Inamdar, Shivangi M., Swaminathan, Swathi, Marenda, Daniel R., Saunders, Aleister J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992708/ https://www.ncbi.nlm.nih.gov/pubmed/35401099 http://dx.doi.org/10.3389/fnins.2022.821059

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