Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro

The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, per...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Anita, Magee, Rachel, Balasubramanian, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992774/
https://www.ncbi.nlm.nih.gov/pubmed/35402897
http://dx.doi.org/10.31487/j.nnb.2020.02.08
_version_ 1784683797664497664
author Singh, Anita
Magee, Rachel
Balasubramanian, Sriram
author_facet Singh, Anita
Magee, Rachel
Balasubramanian, Sriram
author_sort Singh, Anita
collection PubMed
description The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, percentage strain at maximum stress and modulus of elasticity were reported to be 14.6±3.4 N, 0.34±0.11 MPa, 29.3±5.4% and 1.52±0.8 MPa, respectively. These data can help understand the biomechanical behavior of the spinal cord in neonates and can be further used in computational modeling to understand injury mechanisms better and help develop injury prevention strategies.
format Online
Article
Text
id pubmed-8992774
institution National Center for Biotechnology Information
language English
publishDate 2020
record_format MEDLINE/PubMed
spelling pubmed-89927742022-04-08 Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro Singh, Anita Magee, Rachel Balasubramanian, Sriram Neurol Neurobiol (Tallinn) Article The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, percentage strain at maximum stress and modulus of elasticity were reported to be 14.6±3.4 N, 0.34±0.11 MPa, 29.3±5.4% and 1.52±0.8 MPa, respectively. These data can help understand the biomechanical behavior of the spinal cord in neonates and can be further used in computational modeling to understand injury mechanisms better and help develop injury prevention strategies. 2020 2020-05-28 /pmc/articles/PMC8992774/ /pubmed/35402897 http://dx.doi.org/10.31487/j.nnb.2020.02.08 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Singh, Anita
Magee, Rachel
Balasubramanian, Sriram
Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title_full Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title_fullStr Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title_full_unstemmed Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title_short Mechanical Properties of Cervical Spinal Cord in Neonatal Piglet: In Vitro
title_sort mechanical properties of cervical spinal cord in neonatal piglet: in vitro
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992774/
https://www.ncbi.nlm.nih.gov/pubmed/35402897
http://dx.doi.org/10.31487/j.nnb.2020.02.08
work_keys_str_mv AT singhanita mechanicalpropertiesofcervicalspinalcordinneonatalpigletinvitro
AT mageerachel mechanicalpropertiesofcervicalspinalcordinneonatalpigletinvitro
AT balasubramaniansriram mechanicalpropertiesofcervicalspinalcordinneonatalpigletinvitro

Ejemplares similares