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Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones

PURPOSE: Development of an independent MU calculator (StereoCalc) with and without heterogeneity corrections for stereotactic treatments, in a Varian TrueBeam STx LINAC using stereotactic cones, with flattening filter‐free photon energies. METHODS: Multiple depth curves and output factors were measu...

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Autores principales: Campos, Guilherme Filipe Pinto, Souto, Ana Catarina Santos, Lencart, Joana Borges, Cunha, Luís Paulo Teixeira, Dias, Anabela Gregório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992931/
https://www.ncbi.nlm.nih.gov/pubmed/35166027
http://dx.doi.org/10.1002/acm2.13542
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author Campos, Guilherme Filipe Pinto
Souto, Ana Catarina Santos
Lencart, Joana Borges
Cunha, Luís Paulo Teixeira
Dias, Anabela Gregório
author_facet Campos, Guilherme Filipe Pinto
Souto, Ana Catarina Santos
Lencart, Joana Borges
Cunha, Luís Paulo Teixeira
Dias, Anabela Gregório
author_sort Campos, Guilherme Filipe Pinto
collection PubMed
description PURPOSE: Development of an independent MU calculator (StereoCalc) with and without heterogeneity corrections for stereotactic treatments, in a Varian TrueBeam STx LINAC using stereotactic cones, with flattening filter‐free photon energies. METHODS: Multiple depth curves and output factors were measured, following the dosimetry formalism for small fields proposed by the TRS‐483. The developed StereoCalc imports and processes the beam data files and calculates the patient plans with and without heterogeneity correction. Validation of the developed software was carried out using phantoms. The accuracy of the StereoCalc software was verified in stereotactic patient plans. RESULTS: A maximum difference of 2.47% and 2.07% was obtained in the phantom validation tests with and without heterogeneity correction, respectively. The mean percentual difference of StereoCalc from cone dose calculation (CDC) in the clinical testing was 2.86% ±1.27% and 0.78% ±0.48% with and without heterogeneity correction, respectively. The largest differences found were 7.34% and 1.98%, respectively. CONCLUSIONS: The results obtained in this work show that the MU calculated with StereoCalc software is in good agreement with the values calculated by the treatment planning systems, both in static fields and arcs. We have also improved the software to consider heterogeneity corrections calculations. As expected, and as a major achievement of this work, some differences were observed when heterogeneities were considered. StereoCalc proved to be a powerful tool that can be integrated into the specific quality assurance program in a medical physics department for independent verification in stereotactic treatment with cones.
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spelling pubmed-89929312022-04-13 Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones Campos, Guilherme Filipe Pinto Souto, Ana Catarina Santos Lencart, Joana Borges Cunha, Luís Paulo Teixeira Dias, Anabela Gregório J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Development of an independent MU calculator (StereoCalc) with and without heterogeneity corrections for stereotactic treatments, in a Varian TrueBeam STx LINAC using stereotactic cones, with flattening filter‐free photon energies. METHODS: Multiple depth curves and output factors were measured, following the dosimetry formalism for small fields proposed by the TRS‐483. The developed StereoCalc imports and processes the beam data files and calculates the patient plans with and without heterogeneity correction. Validation of the developed software was carried out using phantoms. The accuracy of the StereoCalc software was verified in stereotactic patient plans. RESULTS: A maximum difference of 2.47% and 2.07% was obtained in the phantom validation tests with and without heterogeneity correction, respectively. The mean percentual difference of StereoCalc from cone dose calculation (CDC) in the clinical testing was 2.86% ±1.27% and 0.78% ±0.48% with and without heterogeneity correction, respectively. The largest differences found were 7.34% and 1.98%, respectively. CONCLUSIONS: The results obtained in this work show that the MU calculated with StereoCalc software is in good agreement with the values calculated by the treatment planning systems, both in static fields and arcs. We have also improved the software to consider heterogeneity corrections calculations. As expected, and as a major achievement of this work, some differences were observed when heterogeneities were considered. StereoCalc proved to be a powerful tool that can be integrated into the specific quality assurance program in a medical physics department for independent verification in stereotactic treatment with cones. John Wiley and Sons Inc. 2022-02-15 /pmc/articles/PMC8992931/ /pubmed/35166027 http://dx.doi.org/10.1002/acm2.13542 Text en © 2022 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Campos, Guilherme Filipe Pinto
Souto, Ana Catarina Santos
Lencart, Joana Borges
Cunha, Luís Paulo Teixeira
Dias, Anabela Gregório
Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title_full Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title_fullStr Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title_full_unstemmed Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title_short Development of an independent MU calculation software for radiotherapy treatments with stereotactic cones
title_sort development of an independent mu calculation software for radiotherapy treatments with stereotactic cones
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992931/
https://www.ncbi.nlm.nih.gov/pubmed/35166027
http://dx.doi.org/10.1002/acm2.13542
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