Cargando…

Circulating small RNA signatures differentiate accurately the subtypes of muscular dystrophies: small-RNA next-generation sequencing analytics and functional insights

Muscular dystrophies are a group of rare and severe inherited disorders mainly affecting the muscle tissue. Duchene Muscular Dystrophy, Myotonic Dystrophy types 1 and 2, Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy are some of the members of this family of disorders. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kakouri, Andrea C., Koutalianos, Demetris, Koutsoulidou, Andrie, Oulas, Anastasis, Tomazou, Marios, Nikolenko, Nikoletta, Turner, Chris, Roos, Andreas, Lusakowska, Anna, Janiszewska, Katarzyna, Papadimas, George K., Papadopoulos, Constantinos, Kararizou, Evangelia, Papanicolaou, Eleni Zamba, Gorman, Grainne, Lochmüller, Hanns, Spyrou, George M., Phylactou, Leonidas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993092/ https://www.ncbi.nlm.nih.gov/pubmed/35388741 http://dx.doi.org/10.1080/15476286.2022.2058817

Ejemplares similares

miR-223-3p and miR-24-3p as novel serum-based biomarkers for myotonic dystrophy type 1
por: Koutalianos, Demetris, et al.
Publicado: (2021)

Elevated Muscle-Specific miRNAs in Serum of Myotonic Dystrophy Patients Relate to Muscle Disease Progress
por: Koutsoulidou, Andrie, et al.
Publicado: (2015)

In Silico Identification of Antimicrobial Peptides in the Proteomes of Goat and Sheep Milk and Feta Cheese
por: Tomazou, Marios, et al.
Publicado: (2019)

Bacterial Wars—a tool for the prediction of bacterial predominance based on network analysis measures
por: Oulas, Anastasis, et al.
Publicado: (2023)

Circulating Biomarkers in Muscular Dystrophies: Disease and Therapy Monitoring
por: Koutsoulidou, Andrie, et al.
Publicado: (2020)

Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains
por: Oulas, Anastasis, et al.
Publicado: (2021)

Age-Related Exosomal and Endogenous Expression Patterns of miR-1, miR-133a, miR-133b, and miR-206 in Skeletal Muscles
por: Mytidou, Chrystalla, et al.
Publicado: (2021)

In depth analysis of Cyprus-specific mutations of SARS-CoV-2 strains using computational approaches
por: Oulas, Anastasis, et al.
Publicado: (2021)

Transcriptomic characterization of tissues from patients and subsequent pathway analyses reveal biological pathways that are implicated in spastic ataxia
por: Kakouri, Andrea C., et al.
Publicado: (2022)

PathwayConnector: finding complementary pathways to enhance functional analysis
por: Minadakis, George, et al.
Publicado: (2019)

Selecting variants of unknown significance through network-based gene-association significantly improves risk prediction for disease-control cohorts
por: Oulas, Anastasis, et al.
Publicado: (2019)

Selective Delivery to Cardiac Muscle Cells Using Cell-Specific Aptamers
por: Philippou, Styliana, et al.
Publicado: (2023)

Putative Antimicrobial Peptides Within Bacterial Proteomes Affect Bacterial Predominance: A Network Analysis Perspective
por: Oulas, Anastasis, et al.
Publicado: (2021)

Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington’s Disease Status Based on Omics Data
por: Christodoulou, Christiana C., et al.
Publicado: (2020)

Neurophysiological and Genetic Findings in Patients With Juvenile Myoclonic Epilepsy
por: Stefani, Stefani, et al.
Publicado: (2020)

Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia
por: Constantinou, Andria, et al.
Publicado: (2021)

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle
por: Koutsoulidou, Andrie, et al.
Publicado: (2011)

Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways
por: Kakouri, Andrea C., et al.
Publicado: (2020)

Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches
por: Oulas, Anastasis, et al.
Publicado: (2017)

Twist reverses muscle cell differentiation through transcriptional down-regulation of myogenin
por: Mastroyiannopoulos, Nikolaos P., et al.
Publicado: (2013)

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19
por: Tomazou, Marios, et al.
Publicado: (2021)

Novel clinical, molecular and bioinformatics insights into the genetic background of autism
por: Talli, Ioanna, et al.
Publicado: (2022)

PathWalks: identifying pathway communities using a disease-related map of integrated information
por: Karatzas, Evangelos, et al.
Publicado: (2020)

GnRH Deficient Patients With Congenital Hypogonadotropic Hypogonadism: Novel Genetic Findings in ANOS1, RNF216, WDR11, FGFR1, CHD7, and POLR3A Genes in a Case Series and Review of the Literature
por: Neocleous, Vassos, et al.
Publicado: (2020)

Update on Congenital Myopathies in Adulthood
por: Papadimas, George Konstantinos, et al.
Publicado: (2020)

Integrated Bioinformatics Analysis of Shared Genes, miRNA, Biological Pathways and Their Potential Role as Therapeutic Targets in Huntington’s Disease Stages
por: Christodoulou, Christiana C., et al.
Publicado: (2023)

Intramuscular Evaluation of Chimeric Locked Nucleic Acid/2′OMethyl-Modified Antisense Oligonucleotides for Targeted Exon 23 Skipping in Mdx Mice
por: Georgiadou, Michaella, et al.
Publicado: (2021)

Methylation status of hypothalamic Mkrn3 promoter across puberty
por: Fanis, Pavlos, et al.
Publicado: (2023)

Prediction of novel microRNA genes in cancer-associated genomic regions—a combined computational and experimental approach
por: Oulas, Anastasis, et al.
Publicado: (2009)

Vir2Drug: a drug repurposing framework based on protein similarities between pathogens
por: Minadakis, George, et al.
Publicado: (2022)

An Age-Related Morphometric Profile of Skeletal Muscle in Healthy Untrained Women
por: Bougea, Anastasia, et al.
Publicado: (2016)

Disease burden of myotonic dystrophy type 1
por: Landfeldt, Erik, et al.
Publicado: (2019)

Comparative analysis of affected and unaffected areas of systemic sclerosis skin biopsies by high-throughput proteomic approaches
por: Chairta, Paraskevi, et al.
Publicado: (2020)

Geodemographic Area Classification and Association with Mortality: An Ecological Study of Small Areas of Cyprus
por: Lamnisos, Demetris, et al.
Publicado: (2019)

Analyzing walking speeds with ankle and wrist worn accelerometers in a cohort with myotonic dystrophy
por: Jimenez-Moreno, Aura Cecilia, et al.
Publicado: (2018)

Fibrotic expression profile analysis reveals repurposed drugs with potential anti-fibrotic mode of action
por: Karatzas, Evangelos, et al.
Publicado: (2021)

Highlighting intrafamilial clinical heterogeneity in late-onset Pompe disease()
por: Papadopoulos, C., et al.
Publicado: (2013)

Molecular epidemiology of SARS-CoV-2 in Cyprus
por: Richter, Jan, et al.
Publicado: (2021)

GNE myopathy: from clinics and genetics to pathology and research strategies
por: Pogoryelova, Oksana, et al.
Publicado: (2018)

Mild myopathic phenotype in a patient with homozygous c.416C > T mutation in TK2 gene
por: Papadimas, George K., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gvpj6f5rol0qcq2380f8ckmj3k