LATS1 is a central signal transmitter for achieving full type-I interferon activity

Interferons (IFNs) have broad-spectrum antiviral activity to resist virus epidemic. However, IFN antiviral efficacy needs to be greatly improved. Here, we reveal that LATS1 is a vital signal transmitter governing full type-I IFN (IFN-I) signaling activity. LATS1 constitutively binds with the IFN-I r...

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Detalles Bibliográficos
Autores principales: Zuo, Yibo, He, Jiuyi, Liu, Siying, Xu, Ying, Liu, Jin, Qiao, Caixia, Zang, Lichao, Sun, Wenhuan, Yuan, Yukang, Zhang, Hongguang, Chen, Xiangjie, Jin, Lincong, Miao, Ying, Huang, Fan, Ren, Tengfei, Wang, Jun, Qian, Feng, Zhu, Chuanwu, Zhang, Wei, Liu, Yaobo, Xu, Guoqiang, Ma, Feng, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993116/
https://www.ncbi.nlm.nih.gov/pubmed/35394840
http://dx.doi.org/10.1126/sciadv.abj3887

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