The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-κB signaling

Nasopharyngeal cancer (NPC) is an Epstein-Barr virus (EBV)–positive epithelial malignancy with an extensive inflammatory infiltrate. Traditional RNA-sequencing techniques uncovered only microenvironment signatures, while the gene expression of the tumor epithelial compartment has remained a mystery....

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Detalles Bibliográficos
Autores principales: Tay, Joshua K., Zhu, Chunfang, Shin, June Ho, Zhu, Shirley X., Varma, Sushama, Foley, Joseph W., Vennam, Sujay, Yip, Yim Ling, Goh, Chuan Keng, Wang, De Yun, Loh, Kwok Seng, Tsao, Sai Wah, Le, Quynh-Thu, Sunwoo, John B., West, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993121/
https://www.ncbi.nlm.nih.gov/pubmed/35394843
http://dx.doi.org/10.1126/sciadv.abh2445

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