Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases

A “Leap-of-Faith” approach is used to treat patients with previously unknown ultrarare pathogenic mutations, often based on evidence from patients having dissimilar but more prevalent mutations. This uncertainty reflects the need to develop personalized prescreening platforms for these patients to a...

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Detalles Bibliográficos
Autores principales: Sequiera, Glen Lester, Srivastava, Abhay, Sareen, Niketa, Yan, Weiang, Alagarsamy, Keshav Narayan, Verma, Elika, Aghanoori, Mohamad Reza, Aliani, Michel, Kumar, Ashok, Fernyhough, Paul, Rockman-Greenberg, Cheryl, Dhingra, Sanjiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993122/
https://www.ncbi.nlm.nih.gov/pubmed/35394834
http://dx.doi.org/10.1126/sciadv.abl4370

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