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Single-molecule, quantitative detection of low-abundance somatic mutations by high-throughput sequencing
Postzygotic somatic mutations have been found associated with human disease, including diseases other than cancer. Most information on somatic mutations has come from studying clonally amplified mutant cells, based on a growth advantage or genetic drift. However, almost all somatic mutations are uni...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993124/ https://www.ncbi.nlm.nih.gov/pubmed/35394831 http://dx.doi.org/10.1126/sciadv.abm3259 |