Cargando…
Schema representations in distinct brain networks support narrative memory during encoding and retrieval
Schematic prior knowledge can scaffold the construction of event memories during perception and also provide structured cues to guide memory search during retrieval. We measured the activation of story-specific and schematic representations using fMRI while participants were presented with 16 storie...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993217/ https://www.ncbi.nlm.nih.gov/pubmed/35393941 http://dx.doi.org/10.7554/eLife.70445 |
_version_ | 1784683861364441088 |
---|---|
author | Masís-Obando, Rolando Norman, Kenneth A Baldassano, Christopher |
author_facet | Masís-Obando, Rolando Norman, Kenneth A Baldassano, Christopher |
author_sort | Masís-Obando, Rolando |
collection | PubMed |
description | Schematic prior knowledge can scaffold the construction of event memories during perception and also provide structured cues to guide memory search during retrieval. We measured the activation of story-specific and schematic representations using fMRI while participants were presented with 16 stories and then recalled each of the narratives, and related these activations to memory for specific story details. We predicted that schema representations in medial prefrontal cortex (mPFC) would be correlated with successful recall of story details. In keeping with this prediction, an anterior mPFC region showed a significant correlation between activation of schema representations at encoding and subsequent behavioral recall performance; however, this mPFC region was not implicated in schema representation during retrieval. More generally, our analyses revealed largely distinct brain networks at encoding and retrieval in which schema activation was related to successful recall. These results provide new insight into when and where event knowledge can support narrative memory. |
format | Online Article Text |
id | pubmed-8993217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-89932172022-04-09 Schema representations in distinct brain networks support narrative memory during encoding and retrieval Masís-Obando, Rolando Norman, Kenneth A Baldassano, Christopher eLife Neuroscience Schematic prior knowledge can scaffold the construction of event memories during perception and also provide structured cues to guide memory search during retrieval. We measured the activation of story-specific and schematic representations using fMRI while participants were presented with 16 stories and then recalled each of the narratives, and related these activations to memory for specific story details. We predicted that schema representations in medial prefrontal cortex (mPFC) would be correlated with successful recall of story details. In keeping with this prediction, an anterior mPFC region showed a significant correlation between activation of schema representations at encoding and subsequent behavioral recall performance; however, this mPFC region was not implicated in schema representation during retrieval. More generally, our analyses revealed largely distinct brain networks at encoding and retrieval in which schema activation was related to successful recall. These results provide new insight into when and where event knowledge can support narrative memory. eLife Sciences Publications, Ltd 2022-04-08 /pmc/articles/PMC8993217/ /pubmed/35393941 http://dx.doi.org/10.7554/eLife.70445 Text en © 2022, Masís-Obando et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Masís-Obando, Rolando Norman, Kenneth A Baldassano, Christopher Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title | Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title_full | Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title_fullStr | Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title_full_unstemmed | Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title_short | Schema representations in distinct brain networks support narrative memory during encoding and retrieval |
title_sort | schema representations in distinct brain networks support narrative memory during encoding and retrieval |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993217/ https://www.ncbi.nlm.nih.gov/pubmed/35393941 http://dx.doi.org/10.7554/eLife.70445 |
work_keys_str_mv | AT masisobandorolando schemarepresentationsindistinctbrainnetworkssupportnarrativememoryduringencodingandretrieval AT normankennetha schemarepresentationsindistinctbrainnetworkssupportnarrativememoryduringencodingandretrieval AT baldassanochristopher schemarepresentationsindistinctbrainnetworkssupportnarrativememoryduringencodingandretrieval |