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Dynamic Ca(2+) sensitivity stimulates the evolved SARS-CoV-2 spike strain-mediated membrane fusion for enhanced entry
Mutations in the spike protein generated a highly infectious and transmissible D614G variant, which is present in newly evolved fast-spreading variants. The D614G, Alpha, Beta, and Delta spike variants of SARS-CoV-2 appear to expedite membrane fusion process for entry, but the mechanism of spike-med...
Autores principales: | Singh, Puspangana, Mukherji, Shreya, Basak, Swarnendu, Hoffmann, Markus, Das, Dibyendu Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993541/ https://www.ncbi.nlm.nih.gov/pubmed/35397208 http://dx.doi.org/10.1016/j.celrep.2022.110694 |
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