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Measurements of SARS-CoV-2 antibody dissociation rate constant by chaotrope-free biolayer interferometry in serum of COVID-19 convalescent patients

Kinetics measurements of antigen-antibody binding interactions are critical to understanding the functional efficiency of SARS-CoV-2 antibodies. Previously reported chaotrope-based avidity assays that rely on artificial disruption of binding do not reflect the natural binding kinetics. This study de...

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Detalles Bibliográficos
Autores principales: Hao, Ying, Yang, He S., Karbaschi, Mohsen, Racine-Brzostek, Sabrina E., Li, Pu, Zuk, Robert, Yang, Yawei J., Klasse, P.J., Shi, Yuanyuan, Zhao, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993703/
https://www.ncbi.nlm.nih.gov/pubmed/35447596
http://dx.doi.org/10.1016/j.bios.2022.114237