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Physiological relevance of proton-activated GPCRs
The detection of H(+) concentration variations in the extracellular milieu is accomplished by a series of specialized and non-specialized pH-sensing mechanisms. The proton-activated G protein–coupled receptors (GPCRs) GPR4 (Gpr4), TDAG8 (Gpr65), and OGR1 (Gpr68) form a subfamily of proteins capable...
Autores principales: | Imenez Silva, Pedro H., Wagner, Carsten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993716/ https://www.ncbi.nlm.nih.gov/pubmed/35247105 http://dx.doi.org/10.1007/s00424-022-02671-1 |
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