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HIF-1α-regulated lncRNA-TUG1 promotes mitochondrial dysfunction and pyroptosis by directly binding to FUS in myocardial infarction

Myocardial infarction (MI) is a fatal heart disease that affects millions of lives worldwide each year. This study investigated the roles of HIF-1α/lncRNA-TUG1 in mitochondrial dysfunction and pyroptosis in MI. CCK-8, DHE, lactate dehydrogenase (LDH) assays, and JC-1 staining were performed to measu...

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Detalles Bibliográficos
Autores principales:	Wang, Yong-Wang, Dong, Hong-Zhi, Tan, Yong-Xing, Bao, Xu, Su, Ying-Man, Li, Xin, Jiang, Fang, Liang, Jing, Huang, Zhen-Cai, Ren, Yan-Ling, Xu, Yu-Li, Su, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993815/ https://www.ncbi.nlm.nih.gov/pubmed/35396503 http://dx.doi.org/10.1038/s41420-022-00969-8

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