Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

Mechanical breathing motions have a fundamental function in lung development and disease, but little is known about how they contribute to host innate immunity. Here we use a human lung alveolus chip that experiences cyclic breathing-like deformations to investigate whether physical forces influence...

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Detalles Bibliográficos
Autores principales: Bai, Haiqing, Si, Longlong, Jiang, Amanda, Belgur, Chaitra, Zhai, Yunhao, Plebani, Roberto, Oh, Crystal Yuri, Rodas, Melissa, Patil, Aditya, Nurani, Atiq, Gilpin, Sarah E., Powers, Rani K., Goyal, Girija, Prantil-Baun, Rachelle, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993817/
https://www.ncbi.nlm.nih.gov/pubmed/35396513
http://dx.doi.org/10.1038/s41467-022-29562-4

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