METTL3 stabilizes HDAC5 mRNA in an m(6)A-dependent manner to facilitate malignant proliferation of osteosarcoma cells

Osteosarcoma (OS) is a prevalent primary bone sarcoma. Methyltransferase-like 3 (METTL3) is dysregulated in human malignancies. This study explored the mechanism of METTL3 in OS cell proliferation. Our results demonstrated that METTL3 was highly expressed in OS, and correlated with the tumor size, c...

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Detalles Bibliográficos
Autores principales: Jiang, Renbing, Dai, Zhibing, Wu, Junshen, Ji, Suzhi, Sun, Yachao, Yang, Wenpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993827/
https://www.ncbi.nlm.nih.gov/pubmed/35396379
http://dx.doi.org/10.1038/s41420-022-00926-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993827/
https://www.ncbi.nlm.nih.gov/pubmed/35396379
http://dx.doi.org/10.1038/s41420-022-00926-5

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