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Deciphering how early life adiposity influences breast cancer risk using Mendelian randomization

Studies suggest that adiposity in childhood may reduce the risk of breast cancer in later life. The biological mechanism underlying this effect is unclear but is likely to be independent of body size in adulthood. Using a Mendelian randomization framework, we investigate 18 hypothesised mediators of...

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Detalles Bibliográficos
Autores principales:	Vabistsevits, Marina, Davey Smith, George, Sanderson, Eleanor, Richardson, Tom G., Lloyd-Lewis, Bethan, Richmond, Rebecca C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993830/ https://www.ncbi.nlm.nih.gov/pubmed/35396499 http://dx.doi.org/10.1038/s42003-022-03272-5

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