Cargando…

Prostate cancer polygenic risk score and prediction of lethal prostate cancer

Polygenic risk scores (PRS) for prostate cancer incidence have been proposed to optimize prostate cancer screening. Prediction of lethal prostate cancer is key to any stratified screening program to avoid excessive overdiagnosis. Herein, PRS for incident prostate cancer was evaluated in two populati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klein, Robert J., Vertosick, Emily, Sjoberg, Dan, Ulmert, David, Rönn, Ann-Charlotte, Häggström, Christel, Thysell, Elin, Hallmans, Göran, Dahlin, Anders, Stattin, Pär, Melander, Olle, Vickers, Andrew, Lilja, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993880/ https://www.ncbi.nlm.nih.gov/pubmed/35396534 http://dx.doi.org/10.1038/s41698-022-00266-8

Ejemplares similares

Empirical estimates of prostate cancer overdiagnosis by age and prostate-specific antigen
por: Vickers, Andrew J, et al.
Publicado: (2014)

Prostate Cancer, Prostate Cancer Death, and Death from Other Causes, Among Men with Metabolic Aberrations
por: Häggström, Christel, et al.
Publicado: (2014)

Prostate Cancer Mortality in Areas With High and Low Prostate Cancer Incidence
por: Stattin, Pär, et al.
Publicado: (2014)

Waist circumference and a body shape index and prostate cancer risk and mortality
por: Jochems, Sylvia H. J., et al.
Publicado: (2021)

Influence of blood prostate specific antigen levels at age 60 on benefits and harms of prostate cancer screening: population based cohort study
por: Carlsson, Sigrid, et al.
Publicado: (2014)

Prostate specific antigen for early detection of prostate cancer: longitudinal study
por: Holmström, Benny, et al.
Publicado: (2009)

Prostate Cancer Imaging Trends After a Nationwide Effort to Discourage Inappropriate Prostate Cancer Imaging
por: Makarov, Danil V., et al.
Publicado: (2013)

Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study
por: Vickers, Andrew J, et al.
Publicado: (2013)

Prediagnostic markers of insulin resistance and prostate cancer risk and death: A pooled study
por: Jochems, Sylvia H. J., et al.
Publicado: (2023)

Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer: case-control study
por: Vickers, Andrew J, et al.
Publicado: (2010)

Socioeconomic status and diagnosis, treatment, and mortality in men with prostate cancer. Nationwide population‐based study
por: Tomic, Katarina, et al.
Publicado: (2018)

Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome
por: Hammarsten, Peter, et al.
Publicado: (2019)

Prediction of metastatic prostate cancer by prostate-specific antigen in combination with T stage and Gleason Grade: Nationwide, population-based register study
por: Thomsen, Frederik B., et al.
Publicado: (2020)

High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting
por: Nilsson, Maria, et al.
Publicado: (2015)

Identification of metabolites associated with prostate cancer risk: a nested case-control study with long follow-up in the Northern Sweden Health and Disease Study
por: Röhnisch, Hanna E., et al.
Publicado: (2020)

Metabolomic Characterization of Human Prostate Cancer Bone Metastases Reveals Increased Levels of Cholesterol
por: Thysell, Elin, et al.
Publicado: (2010)

Prospective study of Type 2 diabetes mellitus, anti‐diabetic drugs and risk of prostate cancer
por: Häggström, Christel, et al.
Publicado: (2016)

Association between duration and type of androgen deprivation therapy and risk of diabetes in men with prostate cancer
por: Crawley, Danielle, et al.
Publicado: (2016)

Prostate-specific antigen at or before age 50 as a predictor of advanced prostate cancer diagnosed up to 25 years later: A case-control study
por: Ulmert, David, et al.
Publicado: (2008)

Chronic inflammatory diseases, anti-inflammatory medications and risk of prostate cancer: a population-based case-control study
por: Beckmann, Kerri, et al.
Publicado: (2019)

Identification of prediagnostic metabolites associated with prostate cancer risk by untargeted mass spectrometry‐based metabolomics: A case‐control study nested in the Northern Sweden Health and Disease Study
por: Östman, Johnny R., et al.
Publicado: (2022)

Heterogeneity in risk of prostate cancer: A Swedish population‐based cohort study of competing risks and Type 2 diabetes mellitus
por: Häggström, Christel, et al.
Publicado: (2018)

Addition of Prostate Volume and Prostate-specific Antigen Density to Memorial Sloan Kettering Cancer Center Prostate Cancer Nomograms
por: Tzeng, Michael, et al.
Publicado: (2021)

Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor Growth
por: Halin Bergström, Sofia, et al.
Publicado: (2016)

Cohort Profile Update: The National Prostate Cancer Register of Sweden and Prostate Cancer data Base—a refined prostate cancer trajectory
por: Van Hemelrijck, Mieke, et al.
Publicado: (2016)

Pooled cohort study on height and risk of cancer and cancer death
por: Wirén, Sara, et al.
Publicado: (2013)

Metabolic risk score and cancer risk: pooled analysis of seven cohorts
por: Stocks, Tanja, et al.
Publicado: (2015)

Outcomes in Localized Prostate Cancer: National Prostate Cancer Register of Sweden Follow-up Study
por: Stattin, Pär, et al.
Publicado: (2010)

Genetic risk assessment of lethal prostate cancer using polygenic risk score and hereditary cancer susceptibility genes
por: Ruan, Xiaohao, et al.
Publicado: (2023)

Constrained randomization and multivariate effect projections improve information extraction and biomarker pattern discovery in metabolomics studies involving dependent samples
por: Jonsson, Pär, et al.
Publicado: (2015)

Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor
por: Thysell, Elin, et al.
Publicado: (2019)

Stromal PDGFRβ Expression in Prostate Tumors and Non-Malignant Prostate Tissue Predicts Prostate Cancer Survival
por: Hägglöf, Christina, et al.
Publicado: (2010)

Comparative performance and external validation of the multivariable PREDICT Prostate tool for non-metastatic prostate cancer: a study in 69,206 men from Prostate Cancer data Base Sweden (PCBaSe)
por: Thurtle, David, et al.
Publicado: (2020)

Information on pros and cons of prostate-specific antigen testing to men prior to blood draw: A study from the National Prostate Cancer Register (NPCR) of Sweden
por: Fridriksson, Jon, et al.
Publicado: (2012)

Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancer
por: Srinivasan, Srilakshmi, et al.
Publicado: (2023)

Total Serum Cholesterol and Cancer Incidence in the Metabolic Syndrome and Cancer Project (Me-Can)
por: Strohmaier, Susanne, et al.
Publicado: (2013)

Aggressive rat prostate tumors reprogram the benign parts of the prostate and regional lymph nodes prior to metastasis
por: Strömvall, Kerstin, et al.
Publicado: (2017)

A Prospective Study on Metabolic Risk Factors and Gallbladder Cancer in the Metabolic Syndrome and Cancer (Me-Can) Collaborative Study
por: Borena, Wegene, et al.
Publicado: (2014)

Population-based study on use of chemotherapy in men with castration resistant prostate cancer
por: Lissbrant, Ingela Franck, et al.
Publicado: (2013)

Long-term prediction of prostate cancer diagnosis and death using PSA and obesity related anthropometrics at early middle age: data from the malmö preventive project
por: Assel, Melissa J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_76scbi0e5hahgv36g0aavrehcs