CD157 Can Replace CD24 and CD14 in a Single-Tube Flow-Cytometric Assay to Detect Paroxysmal Nocturnal Hemoglobinuria (PNH) Clones on Both Neutrophils and Monocytes: A Prospective Study From North India

Introduction As per current guidelines, detection of paroxysmal nocturnal hematuria (PNH) clones on leucocytes requires the demonstration of the loss of at least two glycosyl-phosphatidyl-inositol (GPI)-linked molecules on both neutrophils and monocytes by flow cytometry. CD24 and CD14 are GPI-linke...

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Detalles Bibliográficos
Autores principales: Deka, Roopam, Pati, Hara P, Chandra, Dinesh, Manivannan, Prabhu, Chauhan, Richa, Tyagi, Seema, Saxena, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994018/
https://www.ncbi.nlm.nih.gov/pubmed/35415060
http://dx.doi.org/10.7759/cureus.23965

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