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A novel domain within the CIL regulates egress of IFITM3 from the Golgi and reveals a regulatory role of IFITM3 on the secretory pathway

The InterFeron-Induced TransMembrane proteins (IFITMs) are members of the dispanin/CD225 family that act as broad viral inhibitors by preventing viral-to-cellular membrane fusion. In this study, we uncover egress from the Golgi as an important step in the biology of IFITM3 by identifying the domain...

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Detalles Bibliográficos
Autores principales: Zhong, Li, Song, Yuxin, Marziali, Federico, Uzbekov, Rustem, Nguyen, Xuan-Nhi, Journo, Chloé, Roingeard, Philippe, Cimarelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994042/
https://www.ncbi.nlm.nih.gov/pubmed/35396335
http://dx.doi.org/10.26508/lsa.202101174

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