Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation

Saponin-based adjuvants (SBAs) are promising new adjuvants that stand out as they not only enforce CD4 + T cell-mediated immunity and antibody responses, but also induce an unprecedented level of antigen cross-presentation by dendritic cells (DC) and subsequent CD8 + T cell activation. We discovered...

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Detalles Bibliográficos
Autores principales: Huis in ’t Veld, Lisa G. M., Ho, Nataschja I., Wassink, Melisssa, den Brok, Martijn H., Adema, Gosse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994093/
https://www.ncbi.nlm.nih.gov/pubmed/35396971
http://dx.doi.org/10.1007/s00018-022-04253-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994093/
https://www.ncbi.nlm.nih.gov/pubmed/35396971
http://dx.doi.org/10.1007/s00018-022-04253-x

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