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Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation

Saponin-based adjuvants (SBAs) are promising new adjuvants that stand out as they not only enforce CD4 + T cell-mediated immunity and antibody responses, but also induce an unprecedented level of antigen cross-presentation by dendritic cells (DC) and subsequent CD8 + T cell activation. We discovered...

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Detalles Bibliográficos
Autores principales:	Huis in ’t Veld, Lisa G. M., Ho, Nataschja I., Wassink, Melisssa, den Brok, Martijn H., Adema, Gosse J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994093/ https://www.ncbi.nlm.nih.gov/pubmed/35396971 http://dx.doi.org/10.1007/s00018-022-04253-x

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