Cargando…

Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation

PURPOSE: Fibrosis caused by corneal wounding can lead to scar formation, impairing vision. Although preventing fibroblast-to-myofibroblast differentiation has therapeutic potential, effective mechanisms for doing so remain elusive. Recent work shows that mitochondria contribute to differentiation in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeon, Kye-Im, Kumar, Ankita, Wozniak, Kaitlin T., Nehrke, Keith, Huxlin, Krystel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994166/ https://www.ncbi.nlm.nih.gov/pubmed/35377925 http://dx.doi.org/10.1167/iovs.63.4.2

Ejemplares similares

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis
por: Jeon, Kye-Im, et al.
Publicado: (2023)

Inhibition of Human Corneal Myofibroblast Formation
por: Guo, Xiaoqing, et al.
Publicado: (2018)

Corneal myofibroblasts inhibit regenerating nerves during wound healing
por: Jeon, Kye-Im, et al.
Publicado: (2018)

AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye
por: Peng, Fangli, et al.
Publicado: (2022)

Novel Combination BMP7 and HGF Gene Therapy Instigates Selective Myofibroblast Apoptosis and Reduces Corneal Haze In Vivo
por: Gupta, Suneel, et al.
Publicado: (2018)

HC-HA/PTX3 Purified From Human Amniotic Membrane Reverts Human Corneal Fibroblasts and Myofibroblasts to Keratocytes by Activating BMP Signaling
por: Zhu, Ying-Ting, et al.
Publicado: (2020)

Corneal Hydration Control in Fuchs' Endothelial Corneal Dystrophy
por: Wacker, Katrin, et al.
Publicado: (2016)

Endoplasmic Reticulum Stress Disrupts Mitochondrial Bioenergetics, Dynamics and Causes Corneal Endothelial Cell Apoptosis
por: Qureshi, Saba, et al.
Publicado: (2023)

Keratocyte-Derived Myofibroblasts: Functional Differences With Their Fibroblast Precursors
por: Acosta, Ana C., et al.
Publicado: (2023)

A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy
por: Liang, Wentao, et al.
Publicado: (2023)

Topical Pergolide Enhance Corneal Nerve Regrowth Following Induced Corneal Abrasion
por: Zhang, Xiaohui, et al.
Publicado: (2020)

Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population
por: Kaplan, Nihal, et al.
Publicado: (2019)

Corneal Sensitivity and Tear Function in Recurrent Corneal Erosion Syndrome
por: Kang, Eugene Yu-Chuan, et al.
Publicado: (2020)

Goblet Cell Differentiation Potential in Human Corneal Limbal Epithelial Progenitor Cells In Vitro
por: Yokoo, Seiichi, et al.
Publicado: (2020)

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy
por: Wieben, Eric D., et al.
Publicado: (2019)

The Corneal Epithelial Barrier and Its Developmental Role in Isolating Corneal Epithelial and Conjunctival Cells From One Another
por: Kubilus, James K., et al.
Publicado: (2017)

BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium
por: Tiwari, Anil, et al.
Publicado: (2020)

How scars shape the neural landscape: Key molecular mediators of TGF-β1’s anti-neuritogenic effects
por: Jeon, Kye-Im, et al.
Publicado: (2020)

Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium
por: Choi, Moonjung, et al.
Publicado: (2021)

Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium
por: Corliss, Bruce A., et al.
Publicado: (2019)

On the Mechanical Roles of Glycosaminoglycans in the Tensile Properties of Porcine Corneal Stroma
por: Hatami-Marbini, Hamed
Publicado: (2023)

Fuchs' Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy, Type 1
por: Winkler, Nelson S., et al.
Publicado: (2018)

Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing
por: Samaeekia, Ravand, et al.
Publicado: (2018)

Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy
por: Soragni, Elisabetta, et al.
Publicado: (2018)

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts
por: Sriram, Sriniwas, et al.
Publicado: (2017)

Differential Distribution of Laminin N-Terminus α31 Across the Ocular Surface: Implications for Corneal Wound Repair
por: Barrera, Valentina, et al.
Publicado: (2018)

Local Renin-Angiotensin System Activation and Myofibroblast Formation in Graft Versus Host Disease–Associated Conjunctival Fibrosis
por: Shamloo, Kiumars, et al.
Publicado: (2021)

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation
por: Reins, Rose Y., et al.
Publicado: (2016)

Corneal Keratocyte Density and Corneal Nerves Are Reduced in Patients With Severe Obesity and Improve After Bariatric Surgery
por: Iqbal, Zohaib, et al.
Publicado: (2021)

Collagen Remodeling Plays a Pivotal Role in Endothelial Corneal Dystrophies
por: Walckling, Marcus, et al.
Publicado: (2020)

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction
por: Chen, Chen, et al.
Publicado: (2022)

Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump
por: Ogando, Diego G., et al.
Publicado: (2021)

Proteome Composition of Bovine Amniotic Membrane and Its Potential Role in Corneal Healing
por: Capistrano da Silva, Erotides, et al.
Publicado: (2021)

The Role of Elastase in Corneal Epithelial Barrier Dysfunction Caused by Pseudomonas aeruginosa Exoproteins
por: Li, Ye, et al.
Publicado: (2021)

The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF-β1 Expression in the Corneal Epithelium
por: Xu, Jing, et al.
Publicado: (2022)

Effects of Corneal Hydration on Brillouin Microscopy In Vivo
por: Shao, Peng, et al.
Publicado: (2018)

Descemet's Membrane Modulation of Posterior Corneal Fibrosis
por: Medeiros, Carla S., et al.
Publicado: (2019)

Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy
por: Chung, Doug D., et al.
Publicado: (2017)

Dioleoylphosphatidylglycerol Accelerates Corneal Epithelial Wound Healing
por: Bollag, Wendy B., et al.
Publicado: (2020)

Examination of the effects of COVID 19 on corneal endothelium
por: Erdem, Seyfettin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gcsg08kbcq9lam17uj1q5pdl6a