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Effects of reduced gag cleavage efficiency on HIV-1 Gag-Pol package

BACKGROUND: HIV-1 pol, which encodes enzymes required for virus replication, is initially translated as a Gag-Pol fusion protein. Gag-Pol is incorporated into virions via interactions with Gag precursor Pr55(gag). Protease (PR) embedded in Gag-Pol mediates the proteolytic processing of both Pr55gag...

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Detalles Bibliográficos
Autores principales:	Lin, Yi-Ru, Chu, Shih-Ming, Yu, Fu-Hsien, Huang, Kuo-Jung, Wang, Chin-Tien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994222/ https://www.ncbi.nlm.nih.gov/pubmed/35395730 http://dx.doi.org/10.1186/s12866-022-02503-3

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