High ratio of pCXCR4/CXCR4 tumor infiltrating immune cells in primary high grade ovarian cancer is indicative for response to chemotherapy

BACKGROUND: Ovarian cancer (OC) is the fifth most common malignant female cancer with a high mortality, mainly because of aggressive high-grade serous carcinomas (HGSOC), but also due to absence of specific early symptoms and effective detection strategies. The CXCL12-CXCR4 axis is considered to hav...

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Detalles Bibliográficos
Autores principales: Walther, Fabio, Berther, Jana Ladina, Lalos, Alexandros, Ramser, Michaela, Eichelberger, Simone, Mechera, Robert, Soysal, Savas, Muenst, Simone, Posabella, Alberto, Güth, Uwe, Stadlmann, Sylvia, Terracciano, Luigi, Droeser, Raoul A., Zeindler, Jasmin, Singer, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994232/
https://www.ncbi.nlm.nih.gov/pubmed/35397601
http://dx.doi.org/10.1186/s12885-022-09374-x

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