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Human primitive mesenchymal stem cell-derived retinal progenitor cells improved neuroprotection, neurogenesis, and vision in rd12 mouse model of retinitis pigmentosa

BACKGROUND: Currently, there is no treatment for retinal degenerative diseases (RDD) such as retinitis pigmentosa (RP). Stem cell-based therapies could provide promising opportunities to repair the damaged retina and restore vision. Thus far, primarily adult mesenchymal stem cells (MSCs) have been i...

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Detalles Bibliográficos
Autores principales: Brown, Christina, Agosta, Patrina, McKee, Christina, Walker, Keegan, Mazzella, Matteo, Alamri, Ali, Svinarich, David, Chaudhry, G. Rasul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994263/
https://www.ncbi.nlm.nih.gov/pubmed/35395806
http://dx.doi.org/10.1186/s13287-022-02828-w