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The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma

BACKGROUND: N6-methyladenosine (m6A) RNA modification plays a critical role in various physiological and pathological conditions. However, the role of m6A modification in head and neck squamous cell carcinoma (HNSCC) remains elusive. METHODS: In this study, the expression of m6A demethylases was det...

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Detalles Bibliográficos
Autores principales:	Jin, Shufang, Li, Mingyu, Chang, Hanyue, Wang, Ruijie, Zhang, Zhiyuan, Zhang, Jianjun, He, Yue, Ma, Hailong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994291/ https://www.ncbi.nlm.nih.gov/pubmed/35395767 http://dx.doi.org/10.1186/s12943-022-01572-2

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