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β-cell mitochondria in diabetes mellitus: a missing puzzle piece in the generation of hPSC-derived pancreatic β-cells?

Diabetes mellitus (DM), currently affecting 463 million people worldwide is a chronic disease characterized by impaired glucose metabolism resulting from the loss or dysfunction of pancreatic β-cells with the former preponderating in type 1 diabetes (T1DM) and the latter in type 2 diabetes (T2DM). B...

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Detalles Bibliográficos
Autores principales: Diane, Abdoulaye, Al-Shukri, Noora Ali, Bin Abdul Mu-u-min, Razik, Al-Siddiqi, Heba H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994301/
https://www.ncbi.nlm.nih.gov/pubmed/35397560
http://dx.doi.org/10.1186/s12967-022-03327-5