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Past and current status of adolescents living with HIV in South Africa, 2005–2017

OBJECTIVES: This paper reports HIV prevalence, incidence, progress towards the UNAIDS (90-90-90) targets, and HIV drug resistance among adolescents living with HIV in South Africa. We conducted secondary analyses using data extracted from the South African national HIV prevalence surveys (2005–2017)...

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Autores principales: Inbarani, Naidoo, Sinovuyo, Takatshana, Ronel, Sewpaul, Sean, Jooste, Zhou, Siyanai, Goitseone, Maseko, Sizulu, Moyo, Khangelani, Zuma, Musawenkosi, Mabaso, Zungu, Nompumelelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994368/
https://www.ncbi.nlm.nih.gov/pubmed/35397603
http://dx.doi.org/10.1186/s13104-022-06006-2
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author Inbarani, Naidoo
Sinovuyo, Takatshana
Ronel, Sewpaul
Sean, Jooste
Zhou, Siyanai
Goitseone, Maseko
Sizulu, Moyo
Khangelani, Zuma
Musawenkosi, Mabaso
Zungu, Nompumelelo
author_facet Inbarani, Naidoo
Sinovuyo, Takatshana
Ronel, Sewpaul
Sean, Jooste
Zhou, Siyanai
Goitseone, Maseko
Sizulu, Moyo
Khangelani, Zuma
Musawenkosi, Mabaso
Zungu, Nompumelelo
author_sort Inbarani, Naidoo
collection PubMed
description OBJECTIVES: This paper reports HIV prevalence, incidence, progress towards the UNAIDS (90-90-90) targets, and HIV drug resistance among adolescents living with HIV in South Africa. We conducted secondary analyses using data extracted from the South African national HIV prevalence surveys (2005–2017). Analyses were stratified by sex and age (10–14 and 15–19-years), presenting weighted descriptive statistics, and realised totals. RESULTS: HIV prevalence increased from 3.0% in 2012 to 3.7% in 2017, translating to 360 582 (95% CI 302 021-419 144) HIV positive adolescents in 2017. Female adolescents bear a disproportionate HIV burden of 5.6% prevalence versus 0.7% for males. HIV incidence remained relatively stable. For the UNAIDS 90-90-90 targets, approximately 62.3% of adolescents knew their HIV status, 65.4% of whom were on antiretroviral therapy, and of these 78.1% on antiretroviral therapy had attained viral load suppression. There are knowledge gaps pertaining to the magnitude of perinatal infections and postnatal infections, and socio-behavioural risk factors for HIV transmission among adolescents in South Africa. There is still a need for focussed interventions targeting adolescent (1) gender disparities in HIV risk (2) screening for HIV, (3) sustained access and adherence to antiretroviral therapy and (3) retention in care to maintain viral load suppression.
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spelling pubmed-89943682022-04-10 Past and current status of adolescents living with HIV in South Africa, 2005–2017 Inbarani, Naidoo Sinovuyo, Takatshana Ronel, Sewpaul Sean, Jooste Zhou, Siyanai Goitseone, Maseko Sizulu, Moyo Khangelani, Zuma Musawenkosi, Mabaso Zungu, Nompumelelo BMC Res Notes Research Note OBJECTIVES: This paper reports HIV prevalence, incidence, progress towards the UNAIDS (90-90-90) targets, and HIV drug resistance among adolescents living with HIV in South Africa. We conducted secondary analyses using data extracted from the South African national HIV prevalence surveys (2005–2017). Analyses were stratified by sex and age (10–14 and 15–19-years), presenting weighted descriptive statistics, and realised totals. RESULTS: HIV prevalence increased from 3.0% in 2012 to 3.7% in 2017, translating to 360 582 (95% CI 302 021-419 144) HIV positive adolescents in 2017. Female adolescents bear a disproportionate HIV burden of 5.6% prevalence versus 0.7% for males. HIV incidence remained relatively stable. For the UNAIDS 90-90-90 targets, approximately 62.3% of adolescents knew their HIV status, 65.4% of whom were on antiretroviral therapy, and of these 78.1% on antiretroviral therapy had attained viral load suppression. There are knowledge gaps pertaining to the magnitude of perinatal infections and postnatal infections, and socio-behavioural risk factors for HIV transmission among adolescents in South Africa. There is still a need for focussed interventions targeting adolescent (1) gender disparities in HIV risk (2) screening for HIV, (3) sustained access and adherence to antiretroviral therapy and (3) retention in care to maintain viral load suppression. BioMed Central 2022-04-09 /pmc/articles/PMC8994368/ /pubmed/35397603 http://dx.doi.org/10.1186/s13104-022-06006-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Inbarani, Naidoo
Sinovuyo, Takatshana
Ronel, Sewpaul
Sean, Jooste
Zhou, Siyanai
Goitseone, Maseko
Sizulu, Moyo
Khangelani, Zuma
Musawenkosi, Mabaso
Zungu, Nompumelelo
Past and current status of adolescents living with HIV in South Africa, 2005–2017
title Past and current status of adolescents living with HIV in South Africa, 2005–2017
title_full Past and current status of adolescents living with HIV in South Africa, 2005–2017
title_fullStr Past and current status of adolescents living with HIV in South Africa, 2005–2017
title_full_unstemmed Past and current status of adolescents living with HIV in South Africa, 2005–2017
title_short Past and current status of adolescents living with HIV in South Africa, 2005–2017
title_sort past and current status of adolescents living with hiv in south africa, 2005–2017
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994368/
https://www.ncbi.nlm.nih.gov/pubmed/35397603
http://dx.doi.org/10.1186/s13104-022-06006-2
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