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Rapid Development of Autoimmune Hepatitis Secondary to Minocycline
Autoimmune hepatitis (AIH) is a condition that affects the liver which, potentially, may render it fibrotic and eventually cirrhotic. This condition has many etiologies ranging from genetic predispositions and immunological defects to medication and environmental side effects. Essentially, we will e...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994613/ https://www.ncbi.nlm.nih.gov/pubmed/35419249 http://dx.doi.org/10.7759/cureus.23038 |
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author | Rafa, Omar Basile, Eric J Frankini, Elisabeth Ahmed, Ammar |
author_facet | Rafa, Omar Basile, Eric J Frankini, Elisabeth Ahmed, Ammar |
author_sort | Rafa, Omar |
collection | PubMed |
description | Autoimmune hepatitis (AIH) is a condition that affects the liver which, potentially, may render it fibrotic and eventually cirrhotic. This condition has many etiologies ranging from genetic predispositions and immunological defects to medication and environmental side effects. Essentially, we will explore the risks, presentation, diagnosis, and treatment of this condition as it relates to a medication-induced etiology. Here we report a case where a patient developed this condition from taking the antibiotic minocycline. The patient was treated with prednisone therapy and went into complete remission with no reoccurrence of AIH. The purpose of this case report is to highlight the fact that these cases have the potential to occur fairly sooner than expected, in a matter of weeks or months, after the induction of minocycline. Hence, carefully monitoring liver functions more frequently may aide in the prevention of minocycline-induced AIH. |
format | Online Article Text |
id | pubmed-8994613 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-89946132022-04-12 Rapid Development of Autoimmune Hepatitis Secondary to Minocycline Rafa, Omar Basile, Eric J Frankini, Elisabeth Ahmed, Ammar Cureus Gastroenterology Autoimmune hepatitis (AIH) is a condition that affects the liver which, potentially, may render it fibrotic and eventually cirrhotic. This condition has many etiologies ranging from genetic predispositions and immunological defects to medication and environmental side effects. Essentially, we will explore the risks, presentation, diagnosis, and treatment of this condition as it relates to a medication-induced etiology. Here we report a case where a patient developed this condition from taking the antibiotic minocycline. The patient was treated with prednisone therapy and went into complete remission with no reoccurrence of AIH. The purpose of this case report is to highlight the fact that these cases have the potential to occur fairly sooner than expected, in a matter of weeks or months, after the induction of minocycline. Hence, carefully monitoring liver functions more frequently may aide in the prevention of minocycline-induced AIH. Cureus 2022-03-10 /pmc/articles/PMC8994613/ /pubmed/35419249 http://dx.doi.org/10.7759/cureus.23038 Text en Copyright © 2022, Rafa et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Gastroenterology Rafa, Omar Basile, Eric J Frankini, Elisabeth Ahmed, Ammar Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title | Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title_full | Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title_fullStr | Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title_full_unstemmed | Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title_short | Rapid Development of Autoimmune Hepatitis Secondary to Minocycline |
title_sort | rapid development of autoimmune hepatitis secondary to minocycline |
topic | Gastroenterology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994613/ https://www.ncbi.nlm.nih.gov/pubmed/35419249 http://dx.doi.org/10.7759/cureus.23038 |
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