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Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer’s disease

We previously showed that simvastatin (SV) restored memory in a mouse model of Alzheimer disease (AD) concomitantly with normalization in protein levels of memory-related immediate early genes in hippocampal CA1 neurons. Here, we investigated age-related changes in the hippocampal memory pathway, an...

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Detalles Bibliográficos
Autores principales:	Tong, Xin-Kang, Royea, Jessika, Hamel, Edith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994768/ https://www.ncbi.nlm.nih.gov/pubmed/35397630 http://dx.doi.org/10.1038/s41419-022-04784-y

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