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Assessment of the diagnostic and prognostic relevance of ACAT1 and CE levels in plasma, peritoneal fluid and tumor tissue of epithelial ovarian cancer patients - a pilot study

BACKGROUND: Abnormal accumulation of acyl-CoA cholesterol acyltransferase-1 (ACAT1) and ACAT1-mediated cholesterol esterified with fatty acids (CE) contribute to cancer progression in various cancers. Our findings of increased CE and ACAT1 levels in epithelial ovarian cancer (EOC) cell lines prompte...

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Detalles Bibliográficos
Autores principales: Ayyagari, Vijayalakshmi, Li, Maio, Pasman, Zvi, Wang, Xinjia, Louis, Somaja, Diaz-Sylvester, Paula, Groesch, Kathleen, Wilson, Teresa, Brard, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994887/
https://www.ncbi.nlm.nih.gov/pubmed/35399074
http://dx.doi.org/10.1186/s12885-022-09476-6

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