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ProbC: joint modeling of epigenome and transcriptome effects in 3D genome

BACKGROUND: Hi-C and its high nucleosome resolution variant Micro-C provide a window into the spatial packing of a genome in 3D within the cell. Even though both techniques do not directly depend on the binding of specific antibodies, previous work has revealed enriched interactions and domain struc...

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Detalles Bibliográficos
Autor principal: Sefer, Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994916/
https://www.ncbi.nlm.nih.gov/pubmed/35397520
http://dx.doi.org/10.1186/s12864-022-08498-5