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New approaches for the quantification and targeting of noradrenergic dysfunction in Alzheimer's disease
There is clear, early noradrenergic dysfunction in Alzheimer's disease. This is likely secondary to pathological tau deposition in the locus coeruleus, the pontine nucleus that produces and releases noradrenaline, prior to involvement of cortical brain regions. Disruption of noradrenergic pathw...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994981/ https://www.ncbi.nlm.nih.gov/pubmed/35293158 http://dx.doi.org/10.1002/acn3.51539 |