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The regulation of hsacirc_004413 promotes proliferation and drug resistance of gastric cancer cells by acting as a competing endogenous RNA for miR-145-5p

BACKGROUND: Whether circRAN, which acts as a microRNA sponge, plays a role in 5-fluorouracil (5-Fu) resistant gastric cancer has not been reported. In this study, a 5-Fu resistant cell line with an IC50 of 16.59 µM was constructed. METHODS: Using comparative analysis of circRNA in the transcriptomic...

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Detalles Bibliográficos
Autores principales:	Zhou, Fusheng, Ding, Weiqun, Mao, Qiqi, Jiang, Xiaoyun, Chen, Jiajie, Zhao, Xianguang, Xu, Weijia, Huang, Jiaxin, Zhong, Liang, Sun, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995023/ https://www.ncbi.nlm.nih.gov/pubmed/35415017 http://dx.doi.org/10.7717/peerj.12629

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