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Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans

Cisplatin is the most common drug in first-line chemotherapy against solid tumors. We and others have previously used the nematode Caenorhabditis elegans to identify genetic factors influencing the sensitivity and resistance to cisplatin. In this study, we used C. elegans to explore cisplatin effect...

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Detalles Bibliográficos
Autores principales: Martínez-Fernández, Carmen, Bergamino, Milana, Schiavi, Alfonso, Brena, David, Ventura, Natascia, Honnen, Sebastian, Villanueva, Alberto, Nadal, Ernest, Cerón, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995082/
https://www.ncbi.nlm.nih.gov/pubmed/35107130
http://dx.doi.org/10.1242/dmm.049161