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Antimicrobial polymeric composites for high-touch surfaces in healthcare applications

Antimicrobial polymer composites have long been utilized in the healthcare field as part of the first line of defense. These composites are desirable in that they pose a minimal risk of developing contagions with antibiotic resistance. For this reason, the field of antimicrobial composites has seen...

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Autores principales: Liu, Minghui, Bauman, Lukas, Nogueira, Christiane Lourenco, Aucoin, Marc G., Anderson, William A., Zhao, Boxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995198/
https://www.ncbi.nlm.nih.gov/pubmed/35434438
http://dx.doi.org/10.1016/j.cobme.2022.100395
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author Liu, Minghui
Bauman, Lukas
Nogueira, Christiane Lourenco
Aucoin, Marc G.
Anderson, William A.
Zhao, Boxin
author_facet Liu, Minghui
Bauman, Lukas
Nogueira, Christiane Lourenco
Aucoin, Marc G.
Anderson, William A.
Zhao, Boxin
author_sort Liu, Minghui
collection PubMed
description Antimicrobial polymer composites have long been utilized in the healthcare field as part of the first line of defense. These composites are desirable in that they pose a minimal risk of developing contagions with antibiotic resistance. For this reason, the field of antimicrobial composites has seen steady growth over recent years and is becoming increasingly important during the current COVID-19 pandemic. In this article, we first review the need of the antimicrobial polymers in high tough surfaces, the antimicrobial mechanism, and then the recent advances in the development of antimicrobial polymer composite including the utilization of intrinsic antimicrobial polymers, the addition of antimicrobial additives, and new exploration of surface patterning. While there are many established and developing methods of imbuing a material with antimicrobial activity, there currently is no standard quantification method for these properties leading to difficulty comparing the efficacy of these materials within the literature. A discussion of the common antimicrobial characterization methods is provided along with highlights on the need of a standardized quantification of antiviral and antibacterial properties in testing to allow ease of comparison between generated libraries and to facilitate proper screening. We also discuss and comment on the current trends of the development of antimicrobial polymer composites with long-lasting and specific antimicrobial activities, nontoxic properties, and environmental friendliness against a broad-spectrum of microbes.
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spelling pubmed-89951982022-04-11 Antimicrobial polymeric composites for high-touch surfaces in healthcare applications Liu, Minghui Bauman, Lukas Nogueira, Christiane Lourenco Aucoin, Marc G. Anderson, William A. Zhao, Boxin Curr Opin Biomed Eng Article Antimicrobial polymer composites have long been utilized in the healthcare field as part of the first line of defense. These composites are desirable in that they pose a minimal risk of developing contagions with antibiotic resistance. For this reason, the field of antimicrobial composites has seen steady growth over recent years and is becoming increasingly important during the current COVID-19 pandemic. In this article, we first review the need of the antimicrobial polymers in high tough surfaces, the antimicrobial mechanism, and then the recent advances in the development of antimicrobial polymer composite including the utilization of intrinsic antimicrobial polymers, the addition of antimicrobial additives, and new exploration of surface patterning. While there are many established and developing methods of imbuing a material with antimicrobial activity, there currently is no standard quantification method for these properties leading to difficulty comparing the efficacy of these materials within the literature. A discussion of the common antimicrobial characterization methods is provided along with highlights on the need of a standardized quantification of antiviral and antibacterial properties in testing to allow ease of comparison between generated libraries and to facilitate proper screening. We also discuss and comment on the current trends of the development of antimicrobial polymer composites with long-lasting and specific antimicrobial activities, nontoxic properties, and environmental friendliness against a broad-spectrum of microbes. Elsevier Inc. 2022-06 2022-04-11 /pmc/articles/PMC8995198/ /pubmed/35434438 http://dx.doi.org/10.1016/j.cobme.2022.100395 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Liu, Minghui
Bauman, Lukas
Nogueira, Christiane Lourenco
Aucoin, Marc G.
Anderson, William A.
Zhao, Boxin
Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title_full Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title_fullStr Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title_full_unstemmed Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title_short Antimicrobial polymeric composites for high-touch surfaces in healthcare applications
title_sort antimicrobial polymeric composites for high-touch surfaces in healthcare applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995198/
https://www.ncbi.nlm.nih.gov/pubmed/35434438
http://dx.doi.org/10.1016/j.cobme.2022.100395
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