Olive phenols preserve lamin B1 expression reducing cGAS/STING/NFκB‐mediated SASP in ionizing radiation‐induced senescence

Senescence occurs upon critical telomere shortening, or following DNA damage, oncogenic activation, hypoxia and oxidative stress, overall referred to stress‐induced premature senescence (SIPS). In response to DNA damage, senescent cells release cytoplasmic chromatin fragments (CCFs), and express an...

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Detalles Bibliográficos
Autores principales: Frediani, Elena, Scavone, Francesca, Laurenzana, Anna, Chillà, Anastasia, Tortora, Katia, Cimmino, Ilaria, Leri, Manuela, Bucciantini, Monica, Mangoni, Monica, Fibbi, Gabriella, Del Rosso, Mario, Mocali, Alessandra, Giovannelli, Lisa, Margheri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995441/
https://www.ncbi.nlm.nih.gov/pubmed/35278036
http://dx.doi.org/10.1111/jcmm.17255

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