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Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus

T-cells are critically involved in the pathogenesis of systemic lupus erythematosus. Although treatment with the anti-CD3 antibody has been reported to be effective in several autoimmune disease animal models including lupus, the immunosuppressive mechanisms remain obscure because of its pleiotropic...

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Detalles Bibliográficos
Autores principales:	Morita, Masashi, Mizui, Masayuki, Masuyama, Satoshi, Tsokos, George C., Isaka, Yoshitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995471/ https://www.ncbi.nlm.nih.gov/pubmed/35419004 http://dx.doi.org/10.3389/fimmu.2022.855812

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