Cargando…

The Mechanisms of Plasticity of Nociceptive Ion Channels in Painful Diabetic Neuropathy

Treating pain in patients suffering from small fiber neuropathies still represents a therapeutic challenge for health care providers and drug developers worldwide. Unfortunately, none of the currently available treatments can completely reverse symptoms of either gain or loss of peripheral nerve sen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joksimovic, Sonja L., Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pain Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995507/ https://www.ncbi.nlm.nih.gov/pubmed/35419564 http://dx.doi.org/10.3389/fpain.2022.869735

Ejemplares similares

Glycosylation of Ca(V)3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes
por: Joksimovic, Sonja Lj., et al.
Publicado: (2020)

Neurosteroids in Pain Management: A New Perspective on an Old Player
por: Joksimovic, Sonja L., et al.
Publicado: (2018)

Alpha lipoic acid attenuates evoked and spontaneous pain following surgical skin incision in rats
por: Joksimovic, Sonja Lj., et al.
Publicado: (2021)

Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels
por: Tat, Quy L., et al.
Publicado: (2020)

Ca(V)3.2 T-Type Calcium Channels in Peripheral Sensory Neurons Are Important for Mibefradil-Induced Reversal of Hyperalgesia and Allodynia in Rats with Painful Diabetic Neuropathy
por: Obradovic, Aleksandar Lj., et al.
Publicado: (2014)

Is Diabetic Nerve Pain Caused by Dysregulated Ion Channels in Sensory Neurons?
por: Todorovic, Slobodan M.
Publicado: (2015)

The Role of Neuroactive Steroids in Analgesia and Anesthesia: An Interesting Comeback?
por: Jevtovic-Todorovic, Vesna, et al.
Publicado: (2023)

Pharmacological Antagonism of T-Type Calcium Channels Constrains Rebound Burst Firing in Two Distinct Subpopulations of GABA Neurons in the Rat Ventral Tegmental Area: Implications for α-Lipoic Acid
por: Woodward, Taylor Joel, et al.
Publicado: (2019)

Differential effects of the novel neurosteroid hypnotic (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats
por: Joksimovic, Srdjan M., et al.
Publicado: (2021)

Redox and trace metal regulation of ion channels in the pain pathway
por: Evans, J. Grayson, et al.
Publicado: (2015)

General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action
por: Maksimovic, Stefan, et al.
Publicado: (2022)

Neonatal Isoflurane Does Not Affect Sleep Architecture and Minimally Alters Neuronal Beta Oscillations in Adolescent Rats
por: Manzella, Francesca M., et al.
Publicado: (2021)

Editorial: Plasticity of Endogenous Pain Modulatory Circuits in Neuropathy
por: Patel, Ryan, et al.
Publicado: (2021)

Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats
por: Manzella, Francesca M., et al.
Publicado: (2020)

Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH
por: Timic Stamenic, Tamara, et al.
Publicado: (2022)

Inhibition of multiple voltage-gated calcium channels may contribute to spinally mediated analgesia by epipregnanolone in a rat model of surgical paw incision
por: Joksimovic, Sonja Lj., et al.
Publicado: (2019)

Developing brain and general anesthesia – is there a cause for concern?
por: Jevtovic-Todorovic, Vesna
Publicado: (2010)

L-cysteine modulates visceral nociception mediated by the Ca(V)2.3 R-type calcium channels
por: Ghodsi, Seyed Mohammadreza, et al.
Publicado: (2022)

Mechanisms of microbial–neuronal interactions in pain and nociception
por: Lagomarsino, Valentina N., et al.
Publicado: (2020)

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial
por: Meijer, Fleur, et al.
Publicado: (2020)

Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons
por: Cabrera, Omar Hoseá, et al.
Publicado: (2022)

Activation of acid-sensing ion channel 3 by lysophosphatidylcholine 16:0 mediates psychological stress-induced fibromyalgia-like pain
por: Hung, Chih-Hsien, et al.
Publicado: (2020)

Anesthesia and Cancer, Friend or Foe? A Narrative Review
por: Montejano, Julio, et al.
Publicado: (2021)

On determining the mechanical nociceptive threshold in pigs: a reliability study
por: Rettore Andreis, Felipe, et al.
Publicado: (2023)

Investigations into an overlooked early component of painful nociceptive withdrawal reflex responses in humans
por: Thorell, Oumie, et al.
Publicado: (2023)

Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice
por: Latham, Janelle R., et al.
Publicado: (2009)

Nociception in fruit fly larvae
por: Boivin, Jean-Christophe, et al.
Publicado: (2023)

Opioid-induced hyperalgesia: Are thalamic T-type calcium channels treatment targets?
por: Todorovic, Slobodan M.
Publicado: (2022)

Keratinocyte Biomarkers Distinguish Painful Diabetic Peripheral Neuropathy Patients and Correlate With Topical Lidocaine Responsiveness
por: Albrecht, Phillip J., et al.
Publicado: (2021)

Reversal of Neuropathic Pain in Diabetes by Targeting Glycosylation of Ca(v)3.2 T-Type Calcium Channels
por: Orestes, Peihan, et al.
Publicado: (2013)

Propofol-Induced Changes in Neurotrophic Signaling in the Developing Nervous System In Vivo
por: Popic, Jelena, et al.
Publicado: (2012)

Ion Channels of Nociception
por: Giniatullin, Rashid
Publicado: (2020)

Nerve and Vascular Biomarkers in Skin Biopsies Differentiate Painful From Painless Peripheral Neuropathy in Type 2 Diabetes
por: Shillo, Pallai, et al.
Publicado: (2021)

An LPAR(5)-antagonist that reduces nociception and increases pruriception
por: Langedijk, Jacqueline, et al.
Publicado: (2022)

Intraoperative use of the machine learning-derived nociception level monitor results in less pain in the first 90 min after surgery
por: van der Wal, Imeen, et al.
Publicado: (2023)

The T-type calcium channel isoform Ca(v)3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile()
por: Timic Stamenic, Tamara, et al.
Publicado: (2021)

Thalamic T-Type Calcium Channels as Targets for Hypnotics and General Anesthetics
por: Timic Stamenic, Tamara, et al.
Publicado: (2022)

Preservation of thalamic neuronal function may be a prerequisite for pain perception in diabetic neuropathy: A magnetic resonance spectroscopy study
por: Gandhi, Rajiv, et al.
Publicado: (2023)

Anesthesia-Induced Developmental Neurodegeneration: The Role of Neuronal Organelles
por: Jevtovic-Todorovic, Vesna, et al.
Publicado: (2012)

Stress-induced changes in nociceptive responding post-surgery in preclinical rodent models
por: Bella, Ariadni, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_osunpk9ge6951oj4ch7rtckeb4