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Proteogenomic analysis of the autoreactive B cell repertoire in blood and tissues of patients with Sjögren’s syndrome
OBJECTIVE: To comparatively analyse the aberrant affinity maturation of the antinuclear and rheumatoid factor (RF) B cell repertoires in blood and tissues of patients with Sjögren’s syndrome (SjS) using an integrated omics workflow. METHODS: Peptide sequencing of anti-Ro60, anti-Ro52, anti-La and RF...
Autores principales: | Broeren, Mathijs G A, Wang, Jing J, Balzaretti, Giulia, Groenen, Patricia J T A, van Schaik, Barbera D C, Chataway, Tim, Kaffa, Charlotte, Bervoets, Sander, Hebeda, Konnie M, Bounova, Gergana, Pruijn, Ger J M, Gordon, Thomas P, De Vries, Niek, Thurlings, Rogier M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8995816/ https://www.ncbi.nlm.nih.gov/pubmed/35144926 http://dx.doi.org/10.1136/annrheumdis-2021-221604 |
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