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Canagliflozin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Inhibiting NF-κB Signaling and Upregulating Bif-1

NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is an important component of the innate immune system that mediates the secretion of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. However, current studies have shown that the abnormal activation of the NLRP3 i...

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Detalles Bibliográficos
Autores principales:	Niu, Yaoyun, Zhang, Yuehui, Zhang, Wanqiu, Lu, Jinghua, Chen, Yang, Hao, Wenhui, Zhou, Jin, Wang, Lijun, Xie, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996145/ https://www.ncbi.nlm.nih.gov/pubmed/35418866 http://dx.doi.org/10.3389/fphar.2022.820541

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