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Leishmania Major Centrin Gene-Deleted Parasites Generate Skin Resident Memory T-Cell Immune Response Analogous to Leishmanization

Leishmaniasis is a vector-borne parasitic disease transmitted through the bite of a sand fly with no available vaccine for humans. Recently, we have developed a live attenuated Leishmania major centrin gene-deleted parasite strain (LmCen(-/-) ) that induced protection against homologous and heterolo...

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Detalles Bibliográficos
Autores principales: Ismail, Nevien, Karmakar, Subir, Bhattacharya, Parna, Sepahpour, Telly, Takeda, Kazuyo, Hamano, Shinjiro, Matlashewski, Greg, Satoskar, Abhay R., Gannavaram, Sreenivas, Dey, Ranadhir, Nakhasi, Hira L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996177/
https://www.ncbi.nlm.nih.gov/pubmed/35419001
http://dx.doi.org/10.3389/fimmu.2022.864031