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Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report

BACKGROUND: COVID-19 (coronavirus disease 2019) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seriously endangers people's lives. The variation in SARS-CoV-2 makes the research and development of vaccines and specific drugs particularly important. However, the preventio...

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Autores principales: Wu, Xiaoheng, Shen, Min, Quan, Hui, Zhang, Xianqin, Xu, Fengcheng, Li, Juan, He, Miao, Pan, Dongmei, Cao, Ling, Yue, Changwu, Liu, Tianhu, Jia, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996196/
https://www.ncbi.nlm.nih.gov/pubmed/35419368
http://dx.doi.org/10.3389/fmed.2022.828819
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author Wu, Xiaoheng
Shen, Min
Quan, Hui
Zhang, Xianqin
Xu, Fengcheng
Li, Juan
He, Miao
Pan, Dongmei
Cao, Ling
Yue, Changwu
Liu, Tianhu
Jia, Xu
author_facet Wu, Xiaoheng
Shen, Min
Quan, Hui
Zhang, Xianqin
Xu, Fengcheng
Li, Juan
He, Miao
Pan, Dongmei
Cao, Ling
Yue, Changwu
Liu, Tianhu
Jia, Xu
author_sort Wu, Xiaoheng
collection PubMed
description BACKGROUND: COVID-19 (coronavirus disease 2019) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seriously endangers people's lives. The variation in SARS-CoV-2 makes the research and development of vaccines and specific drugs particularly important. However, the prevention and diagnosis of COVID-19 cannot be underestimated in the control of the epidemic. CASE PRESENTATION: We introduced a 65-year-old female patient who was diagnosed with COVID-19. The SARS-CoV-2 nucleic acid test result of this patient was positive again during treatment. It took 85 days from the first symptom to the final cure. According to the known reports, she is currently the patient with the longest virus shedding in Sichuan Province, China. Due to the patient's special condition, she was treated in four hospitals before and after, and she was diagnosed with type 2 diabetes mellitus (T2DM) and right lung metastatic adenocarcinoma. We fully introduced the patient's epidemiological history, diagnosis, testing, and treatment process. The patient was finally discharged from the hospital under the treatment of antiviral, hypoglycaemic, anti-anxiety, and a combination of Chinese and Western medicine. CONCLUSIONS: The epidemic is still rampant, and we should not relax our efforts in the prevention and control of viruses. For the elderly, especially those who are suffering from complications or vulnerable to diseases, it is recommended to extend the observation time. Additionally, medical workers should pay attention to the mental state of patients.
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spelling pubmed-89961962022-04-12 Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report Wu, Xiaoheng Shen, Min Quan, Hui Zhang, Xianqin Xu, Fengcheng Li, Juan He, Miao Pan, Dongmei Cao, Ling Yue, Changwu Liu, Tianhu Jia, Xu Front Med (Lausanne) Medicine BACKGROUND: COVID-19 (coronavirus disease 2019) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seriously endangers people's lives. The variation in SARS-CoV-2 makes the research and development of vaccines and specific drugs particularly important. However, the prevention and diagnosis of COVID-19 cannot be underestimated in the control of the epidemic. CASE PRESENTATION: We introduced a 65-year-old female patient who was diagnosed with COVID-19. The SARS-CoV-2 nucleic acid test result of this patient was positive again during treatment. It took 85 days from the first symptom to the final cure. According to the known reports, she is currently the patient with the longest virus shedding in Sichuan Province, China. Due to the patient's special condition, she was treated in four hospitals before and after, and she was diagnosed with type 2 diabetes mellitus (T2DM) and right lung metastatic adenocarcinoma. We fully introduced the patient's epidemiological history, diagnosis, testing, and treatment process. The patient was finally discharged from the hospital under the treatment of antiviral, hypoglycaemic, anti-anxiety, and a combination of Chinese and Western medicine. CONCLUSIONS: The epidemic is still rampant, and we should not relax our efforts in the prevention and control of viruses. For the elderly, especially those who are suffering from complications or vulnerable to diseases, it is recommended to extend the observation time. Additionally, medical workers should pay attention to the mental state of patients. Frontiers Media S.A. 2022-03-28 /pmc/articles/PMC8996196/ /pubmed/35419368 http://dx.doi.org/10.3389/fmed.2022.828819 Text en Copyright © 2022 Wu, Shen, Quan, Zhang, Xu, Li, He, Pan, Cao, Yue, Liu and Jia. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Wu, Xiaoheng
Shen, Min
Quan, Hui
Zhang, Xianqin
Xu, Fengcheng
Li, Juan
He, Miao
Pan, Dongmei
Cao, Ling
Yue, Changwu
Liu, Tianhu
Jia, Xu
Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title_full Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title_fullStr Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title_full_unstemmed Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title_short Shedding of SARS-CoV-2 for 85 Days in COVID-19 Patients With Type 2 Diabetes Mellitus and Lung Metastasis: A Case Report
title_sort shedding of sars-cov-2 for 85 days in covid-19 patients with type 2 diabetes mellitus and lung metastasis: a case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996196/
https://www.ncbi.nlm.nih.gov/pubmed/35419368
http://dx.doi.org/10.3389/fmed.2022.828819
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