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Filling in the gaps: SNX-RGS proteins as multiorganelle tethers
SNX-RGS proteins are molecular tethers localized to multiple interorganelle contact sites that exhibit roles in cellular metabolism. Here, we highlight recent findings on these proteins and discuss their emerging roles in metabolism, human disease, and lipid trafficking.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996316/ https://www.ncbi.nlm.nih.gov/pubmed/35389422 http://dx.doi.org/10.1083/jcb.202203061 |
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author | Hariri, Hanaa Henne, W. Mike |
author_facet | Hariri, Hanaa Henne, W. Mike |
author_sort | Hariri, Hanaa |
collection | PubMed |
description | SNX-RGS proteins are molecular tethers localized to multiple interorganelle contact sites that exhibit roles in cellular metabolism. Here, we highlight recent findings on these proteins and discuss their emerging roles in metabolism, human disease, and lipid trafficking. |
format | Online Article Text |
id | pubmed-8996316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-89963162022-11-02 Filling in the gaps: SNX-RGS proteins as multiorganelle tethers Hariri, Hanaa Henne, W. Mike J Cell Biol Viewpoint SNX-RGS proteins are molecular tethers localized to multiple interorganelle contact sites that exhibit roles in cellular metabolism. Here, we highlight recent findings on these proteins and discuss their emerging roles in metabolism, human disease, and lipid trafficking. Rockefeller University Press 2022-04-07 /pmc/articles/PMC8996316/ /pubmed/35389422 http://dx.doi.org/10.1083/jcb.202203061 Text en © 2022 Hariri and Henne https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Viewpoint Hariri, Hanaa Henne, W. Mike Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title | Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title_full | Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title_fullStr | Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title_full_unstemmed | Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title_short | Filling in the gaps: SNX-RGS proteins as multiorganelle tethers |
title_sort | filling in the gaps: snx-rgs proteins as multiorganelle tethers |
topic | Viewpoint |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996316/ https://www.ncbi.nlm.nih.gov/pubmed/35389422 http://dx.doi.org/10.1083/jcb.202203061 |
work_keys_str_mv | AT haririhanaa fillinginthegapssnxrgsproteinsasmultiorganelletethers AT hennewmike fillinginthegapssnxrgsproteinsasmultiorganelletethers |