Cargando…

Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma

BACKGROUND: The purpose of this paper was to compare the clinical effects of acute shortening and re-lengthening (ASR) technique with antibiotic calcium sulfate-loaded bone transport (ACSBT) technique for the management of large segmental tibial defects after trauma. METHODS: In this retrospective s...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Qiang, Xu, YiBo, Lu, Yao, Ren, Cheng, Liu, Lu, Li, Ming, Wang, Qian, Li, Zhong, Xue, HanZhong, Zhang, Kun, Ma, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996420/
https://www.ncbi.nlm.nih.gov/pubmed/35399099
http://dx.doi.org/10.1186/s13018-022-03109-1
_version_ 1784684487109509120
author Huang, Qiang
Xu, YiBo
Lu, Yao
Ren, Cheng
Liu, Lu
Li, Ming
Wang, Qian
Li, Zhong
Xue, HanZhong
Zhang, Kun
Ma, Teng
author_facet Huang, Qiang
Xu, YiBo
Lu, Yao
Ren, Cheng
Liu, Lu
Li, Ming
Wang, Qian
Li, Zhong
Xue, HanZhong
Zhang, Kun
Ma, Teng
author_sort Huang, Qiang
collection PubMed
description BACKGROUND: The purpose of this paper was to compare the clinical effects of acute shortening and re-lengthening (ASR) technique with antibiotic calcium sulfate-loaded bone transport (ACSBT) technique for the management of large segmental tibial defects after trauma. METHODS: In this retrospective study, 68 patients with large segmental tibial defects were included and completely followed. The bone loss was 3–10 cm. ASR group included 32 patients, while ACSBT group contained 36. There was no significant difference in demographic information between the two groups. The external fixation time (EFT) and external fixation index (EFI) were compared. Bone defect healing and limb functions were evaluated according to the Association for the Study and Application of the Method of Ilizarov (ASAMI) criteria. Complications were compared by Paley classification. RESULTS: The mean EFT was 9.2 ± 1.8 months in ASR group and 10.1 ± 2.0 months in ACSBT group, respectively. The mean EFI was 1.5 ± 0.2 month/cm and 1.4 ± 0.3 month/cm. According to the ASAMI criteria, in ASR group bone defect healing was excellent in 22 cases, good in 7 cases and fair in 3 cases. In ACSBT group, it was excellent in 23 cases, good in 11 cases and fair in 2 cases. In ASR group, the limb function was excellent in 15 cases, good in 7 cases and fair in 10 cases, while it was excellent in 14 cases, good in 9 cases and fair in 13 cases with ACSBT group. There was no significant difference in EFI, bone defect healing and limb functions between the two groups (p > 0.05). The mean number of complications per patient in ACSBT group was significantly lower than that in ASR group (p < 0.05). CONCLUSION: Both techniques can be successfully used for the management of large segmental tibial defects after trauma. There was no significant difference in EFI, limb functions and bone defect healing between the two groups. Compared with ASR group, the complication incidence in ACSBT group was lower, especially the infection-related complications. Therefore, for patients with large segmental bone defects caused by infection or osteomyelitis, ACSBT technique could be the first choice.
format Online
Article
Text
id pubmed-8996420
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-89964202022-04-12 Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma Huang, Qiang Xu, YiBo Lu, Yao Ren, Cheng Liu, Lu Li, Ming Wang, Qian Li, Zhong Xue, HanZhong Zhang, Kun Ma, Teng J Orthop Surg Res Research Article BACKGROUND: The purpose of this paper was to compare the clinical effects of acute shortening and re-lengthening (ASR) technique with antibiotic calcium sulfate-loaded bone transport (ACSBT) technique for the management of large segmental tibial defects after trauma. METHODS: In this retrospective study, 68 patients with large segmental tibial defects were included and completely followed. The bone loss was 3–10 cm. ASR group included 32 patients, while ACSBT group contained 36. There was no significant difference in demographic information between the two groups. The external fixation time (EFT) and external fixation index (EFI) were compared. Bone defect healing and limb functions were evaluated according to the Association for the Study and Application of the Method of Ilizarov (ASAMI) criteria. Complications were compared by Paley classification. RESULTS: The mean EFT was 9.2 ± 1.8 months in ASR group and 10.1 ± 2.0 months in ACSBT group, respectively. The mean EFI was 1.5 ± 0.2 month/cm and 1.4 ± 0.3 month/cm. According to the ASAMI criteria, in ASR group bone defect healing was excellent in 22 cases, good in 7 cases and fair in 3 cases. In ACSBT group, it was excellent in 23 cases, good in 11 cases and fair in 2 cases. In ASR group, the limb function was excellent in 15 cases, good in 7 cases and fair in 10 cases, while it was excellent in 14 cases, good in 9 cases and fair in 13 cases with ACSBT group. There was no significant difference in EFI, bone defect healing and limb functions between the two groups (p > 0.05). The mean number of complications per patient in ACSBT group was significantly lower than that in ASR group (p < 0.05). CONCLUSION: Both techniques can be successfully used for the management of large segmental tibial defects after trauma. There was no significant difference in EFI, limb functions and bone defect healing between the two groups. Compared with ASR group, the complication incidence in ACSBT group was lower, especially the infection-related complications. Therefore, for patients with large segmental bone defects caused by infection or osteomyelitis, ACSBT technique could be the first choice. BioMed Central 2022-04-10 /pmc/articles/PMC8996420/ /pubmed/35399099 http://dx.doi.org/10.1186/s13018-022-03109-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Huang, Qiang
Xu, YiBo
Lu, Yao
Ren, Cheng
Liu, Lu
Li, Ming
Wang, Qian
Li, Zhong
Xue, HanZhong
Zhang, Kun
Ma, Teng
Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title_full Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title_fullStr Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title_full_unstemmed Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title_short Acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
title_sort acute shortening and re-lengthening versus antibiotic calcium sulfate-loaded bone transport for the management of large segmental tibial defects after trauma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996420/
https://www.ncbi.nlm.nih.gov/pubmed/35399099
http://dx.doi.org/10.1186/s13018-022-03109-1
work_keys_str_mv AT huangqiang acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT xuyibo acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT luyao acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT rencheng acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT liulu acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT liming acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT wangqian acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT lizhong acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT xuehanzhong acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT zhangkun acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma
AT mateng acuteshorteningandrelengtheningversusantibioticcalciumsulfateloadedbonetransportforthemanagementoflargesegmentaltibialdefectsaftertrauma