B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer

INTRODUCTION: B7-H4 is overexpressed in colorectal cancer (CRC) and plays an important role in tumor growth and immunosuppression. However, the exact mechanism that regulates B7-H4 expression remains largely unknown. Here, we investigated whether protein kinase C δ (PKCδ) regulates the expression of...

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Detalles Bibliográficos
Autores principales: Zhou, Bin, Lu, Youwei, Zhao, Zhiming, Shi, Tongguo, Wu, Hongya, Chen, Weichang, Zhang, Liang, Zhang, Xueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996430/
https://www.ncbi.nlm.nih.gov/pubmed/35410218
http://dx.doi.org/10.1186/s12935-022-02567-1

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