Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2

Developing strategies against the SARS-CoV-2 is currently a main research subject. SARS-CoV-2 infects host cells by binding to human ACE2 receptors. Both, virus and ACE2, are highly glycosylated, and exploiting glycans of the SARS-CoV-2 envelope as binding sites for ACE2 represents a virus strategy...

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Detalles Bibliográficos
Autores principales: Francesconi, Oscar, Donnici, Lorena, Fragai, Marco, Pesce, Elisa, Bombaci, Mauro, Fasciani, Alessandra, Manganaro, Lara, Conti, Matteo, Grifantini, Renata, De Francesco, Raffaele, Nativi, Cristina, Roelens, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996466/
https://www.ncbi.nlm.nih.gov/pubmed/35434540
http://dx.doi.org/10.1016/j.isci.2022.104239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996466/
https://www.ncbi.nlm.nih.gov/pubmed/35434540
http://dx.doi.org/10.1016/j.isci.2022.104239

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