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Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

The conformational landscape of a protein is constantly expanded by genetic variations that have a minimal impact on the function(s) while causing subtle effects on protein structure. The wider the conformational space sampled by these variants, the higher the probabilities to adapt to changes in en...

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Detalles Bibliográficos
Autores principales:	Dindo, Mirco, Pascarelli, Stefano, Chiasserini, Davide, Grottelli, Silvia, Costantini, Claudio, Uechi, Gen‐Ichiro, Giardina, Giorgio, Laurino, Paola, Cellini, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Full‐length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996469/ https://www.ncbi.nlm.nih.gov/pubmed/35481644 http://dx.doi.org/10.1002/pro.4303

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